After gettin few questions that when will we support TFS2010 on our TFS Bug Item Synchronizer we did some trial on it using TFS2010 Beta 2.
And the answer is that yes, we can support this already today using TFS2008 SP1 client.
We will add support also for native TFS2010 Explorer and support for TFS2005 and TFS2008 will still be there as well.